You will have breathing troubles or withdrawal signs and symptoms if You begin or quit using specific other medicines. Convey to your medical professional if Additionally you use an antibiotic, antifungal medication, heart or blood pressure medication, seizure medication, or medication to treat HIV or hepatitis C.
Speak with your care workforce about the usage of this medication in little ones. Specific treatment can be desired. This medication shouldn't be specified to infants and children younger than 2 many years aged.
Promethazine also has long been shown to get immunosuppressive activity in animals. Whilst some facts instructed that the drug may lessen the variety and function of fetal T-cells when administered chronically in the course of pregnancy, other information suggest the drug doesn't have an effect on the number of fetal T- or B-cells; further more scientific tests within the prospective effects of promethazine on fetal immunocompetence are essential.
Promethazine hydrochloride is additive with or may possibly potentiate the sedative and respiratory depressant actions of opiates or other analgesics along with other CNS depressants like barbiturates or other sedatives, antihistamines, tranquilizers, or Alcoholic beverages.
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Standard Grownup dosage is 50 mg promethazine hydrochloride tablets, USP using an properly diminished dose of narcotic or barbiturate plus the needed level of a belladonna alkaloid.
As an antihistamine, promethazine hydrochloride normally is specified at bedtime due to its pronounced sedative results. The usual adult oral dose of promethazine hydrochloride click here is 25 mg just before retiring; if important, having said that, twelve.five mg might be administered right before foods and on retiring.
Phenylephrine is contraindicated in individuals with hypertension or with peripheral vascular insufficiency (ischemia could result with risk of gangrene orthrombosis of compromised vascular beds).
Thing to consider must be offered to the discontinuation of promethazine hydrochloride also website to the use of other prescription drugs if these reactions arise. Respiratory depression, nightmares, delirium, and agitated behavior have also been described in some of these clients.
Antihistamines, which includes promethazine, are already fetocidal in rodents, even so the pharmacologic results of histamine in rodents differ from Those people in human beings. Promethazine has become documented to probably ameliorate get more info the consequences of hemolytic disorder with the newborn† [off-label] (erythroblastosis fetalis) when administered throughout pregnancy in Rh-sensitized women, but the security and efficacy in the drug for this use haven't been Plainly set up; other ways of management are preferred. Promethazine should be applied in the course of pregnancy only when the probable Rewards justify the possible pitfalls towards the fetus.
Promethazine DM is employed when wanted. If you promethazine for sale are get more info on the dosing plan, skip any skipped dose. Will not use two doses at one time.